I am a big fan of Firefox and have been using it for quite a while. One of the things that I love about Firefox is the ability to customize it using extensions. A few months ago, I wrote a post where I discussed my favorite Firefox extensions.
Lifehacker has a post that talks about the great features of Firefox that are built into the program, the stuff you can do without adding any extensions.
My favorites from the list are Tweakable search engines and Undo closed tab.
Many times I have accidentally closed a tab before I intended to. The Undo closed tab feature is a real lifesaver in those situations.
Check out the entire list. To find out more about a particular feature, click on its name in the list.